|Gene regulation and metabolism : postgenomic computational approaches|
Collado-Vides, Julio and Hofestadt, Ralf Eds. Cambridge, MA US ; London, GB : The MIT Press, 2002. X-310 p. ; 24 cm. (Computational molecular biology) 0-262-03297-X
From the cover : As exciting as the new field of genomics is, it has not yet produced a basic conceptual change in biology. The fundamental problems remain: the origin of life, cell organization, the pathways of differentiation, aging, and the molecular and cellular capabilities of the brain. What has occurred is an explosion of molecular information obtained by genornic sequences, which will soon be followed by exhaustive catalogs of protein interactions and protein function. This wealth of information can be analyzed and manipulated only with the help of computers. The rapidly expanding role of computers in biology may usher in a profound conceptual change in how we study living systerns in the laboratory.
This book focuses on computational approaches to understanding the complex networks of metabolic and gene regulatory capabilities of the cell. The contributors look wellbeyond the state of the art in computational biology to anticipate what biological research will be like in a postgenomic world.