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								|  | Dealing with discontinuities in the qualitative simulation of genetic regulatory networks |  |  |  |  |  
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								|  |  | Proceedings of 15th European Conference on Artifical Intelligence, ECAI 2002, pp. 412-416, IOS Press, Amsterdam, 2002 |  
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					| H. de Jong, J.-L. Gouzé, C. Hernandez, M. Page, T. Sari, J. Geiselmann |  
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								| Methods developed for the qualitative simulation of dynamical systems have turned out to be powerful tools for studying genetic regulatory networks. We present a generalization of a simulation method based on piecewise-linear differential equation models that is able to deal with discontinuities. The method is sound and has been implemented in a computer tool called GNA.  |  |  |  |