June 28th, 2004 : GNA 5.5 is available

GNA (Genetic Network Analyzer) is a computer tool for the modeling and simulation of genetic regulatory networks. The aim of GNA is to assist biologists and bioinformaticians in constructing a model of a regulatory network using knowledge about regulatory interactions in combination with gene expression data.

At present, GNA consists of a simulator of qualitative models of genetic regulatory networks in the form of piecewise-linear differential equations. The simulator has been implemented in Java 1.4 and has been applied to the analysis of various regulatory systems, including the network controlling the initiation of sporulation in B. subtilis.

GNA has been developed by Hidde de Jong and Michel Page of the Helix research group. Grégory Batt (INRIA Rhône-Alpes), Hans Geiselmann (Université Joseph Fourier, Grenoble), Céline Hernandez (now at SIB), Jean-Luc Gouzé (INRIA Sophia-Antipolis), Delphine Ropers (INRIA Rhône-Alpes), Tewfik Sari (Université de Mulhouse), and Dominique Schneider (Université Joseph Fourier, Grenoble) have made important contributions to the development of the qualitative simulation method underlying GNA as well as to the application of the tool.

GNA is available for non-profit academic research purposes. If you want to obtain GNA, please consult the GNA web site or send an email to Hidde de Jong.