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ROSO: optimizing oligonucleotide probes for microarrays
Bioinformatics. 2004 Jan. 20(2):271-273
N. Reymond, H. Charles, L. Duret, F. Calevro, G. Beslon, J.-M. Fayard


ROSO is a software to design optimal oligonucleotide probe sets for microarrays. Selected probes show no significant cross-hybridization, no stable secondary structures and their Tm are chosen to minimize the Tm variability of the probe set.

Availability: The program is available on the internet. Sources are freely available, for non-profit use, on request to the authors. Supplementary information:

PMID: 14734320

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