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Modeling and simulation of genetic regulatory networks |
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A gene is said to be expressed when the information it contains is used by the cellular machinery to produce RNAs or proteins. The expression of a gene may be under the control of other genes: the binding of proteins to specific DNA regions located in the neighborhood of a gene leads to the inhibition or the activation of its expression. Genes are thus involved in complex networks of regulatory interactions. In order to obtain an understanding of the dynamics of these networks, computer modeling and simulation are required. |
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