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Dealing with discontinuities in the qualitative simulation of genetic regulatory networks
Working Notes of 16th International Workshop on Qualitative Reasoning, QR 2002, Sitges, Barcelona, 67-74, 2002
H. de Jong, J.-L. Gouzé, C. Hernandez, M. Page, T. Sari, J. Geiselmann

Methods developed for the qualitative simulation of dynamical systems have turned out to be powerful tools for studying genetic regulatory networks. We present a generalization of a simulation method based on piecewise-linear differential equation models that is able to deal with discontinuities. The method is sound and has been implemented in a computer tool called GNA.

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